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KAT6A Promotes Lung Cancer Proliferation and Invasion via Keap1‐Nrf2 Signaling复制

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Q Ning, W Bai, H Li, J Xue, D Li, T Chen
Advanced Biology, 2026
Wiley Online Library
This study aimed to investigate the role of lysine acetyltransferase 6A (KAT6A) in lung cancer progression and its potential involvement in Nrf2‐related oxidative stress regulation. KAT6A was overexpressed or silenced in A549 and H1299 lung cancer cells. KAT6A expression was verified by quantitative reverse transcription polymerase chain reaction and Western blot. Cell Counting Kit‐8 and Transwell assays showed that KAT6A overexpression promoted cell proliferation and invasion, whereas KAT6A silencing suppressed cell …

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