Efficacy and Safety of Centanafadine in Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
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MA Muneer, M Naveed, M Amjad, M Sarfraz…
Psychopharmacology …, 2026
europepmc.org
Background Attention-deficit/hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder associated with persistent functional impairment across the lifespan. Although several pharmacological treatments are available, their clinical utility is often limited by tolerability concerns, heterogeneous efficacy, and limited long-term safety data. Centanafadine, a novel triple monoamine reuptake inhibitor targeting norepinephrine, dopamine, and serotonin transporters, has emerged as a potential non-stimulant treatment …
