期刊论文这篇文献的Supplementary materials ：A combined approach for full API particle size distribution characterization in nasal spray suspensions based on their dissolution behavior复制

DOI:复制

文献链接:复制

其他信息:

Y Cheng, H Shu, Y Zhang, L Qin, R Chen…
Journal of Pharmaceutical …, 2026
Elsevier
Determining the particle size distribution (PSD) of the active pharmaceutical ingredient (API) in nasal spray suspensions is a challenging task that usually requires the use of morphologically-directed Raman spectroscopy (MDRS). A dissolution-based modeling strategy was established to characterize the entire PSD of starting API in mometasone furoate nasal sprays using dissolution data of finished formulations, whereas MDRS measures API PSD in the final products. A dissolution-PSD model was built in-house to …