期刊论文Antiarthritic effects of glucosamine sulfate studied in animal models.复制

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I Setnikar, MA Pacini, L Revel
Arzneimittel-forschung, 1991
europepmc.org
The antireactive activity of glucosamine sulfate (GS)(CAS 29031-19-4) was tested in the rat in experimental models of subacute inflammation (sponge granuloma and croton oil granuloma), on subacute mechanical arthritis (kaolin arthritis) and in immunological-reactive arthritis and generalized inflammation (adjuvant arthritis). On these models GS was found effective in oral daily doses of 50-800 mg/kg. Tne potency of GS in comparison of that of indometacin used in the same tests as reference substance was found 50-300 times lower …