Patents on AI-derived drugs: empirical evidence and legal challenges: Patents
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J Freilich, AK Rai
nature biotechnology, 2026
nature.com
… Accordingly, in this article we consider patents on AI-derived drugs both as sources of new evidence on scientific progress and from a legal standpoint. On the evidentiary end, we extract drug structures and therapeutic targets from patents filed by AI-native firms and compare them across several dimensions to matched, non-AI-derived controls. We find that an AI-derived drug is more likely than a matched control to have a combination of new therapeutic target and structural distinctiveness as compared to existing drugs, suggesting a …

