Development and functional assessment of a broad-spectrum cryoprotectant for preserving next-generation probiotics
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ME Gorji, W Li, D Zhao
Food Research International, 2026
Elsevier
AbstractWhile next-generation probiotics (NGPs) are increasingly recognized for their health benefits, their incorporation into food products is severely hindered by challenges in preservation. Freeze-drying (lyophilization) is the standard method for preserving probiotics, yet oxygen exposure and freeze-drying stresses substantially reduce bacterial survival rates, particularly for anaerobic probiotics. In this study, we developed a broad-spectrum lyophilization medium (LM) for both conventional and next-generation probiotics. The …

