A comparison of current methods to measure antibodies in type 1 diabetes
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M Infantino, M Manfredi, E Garrafa…
Clinical Chemistry …, 2025
degruyterbrill.com
Abstract Objectives Type 1 diabetes (T1D) is a chronic autoimmune disease causing β-cell destruction, hyperglycemia, and lifelong insulin dependence that can lead to severe complications like ketoacidosis, with a 1% mortality rate in newly diagnosed patients. A significant breakthrough in T1D research was the identification of a long presymptomatic phase, characterized by disease-specific autoantibodies despite the absence of clinical symptoms. The aim of our study was to compare the results of different commercial assays …
