Regioselective Pd-Catalyzed C1–H Acylation of Carbazoles via Pd/Norbornene Cooperative Catalysis
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F Herington, FJ Achal, D Figueroa-Agosto…
The Journal of …, 2025
ACS Publications
Carbazole scaffolds exhibit diverse applications in materials and biomedical research. We report here a regioselective acylation reaction of carbazole derivatives via a six-membered palladacycle intermediate, featuring the broad functional group compatibility and unique regioselectivity. Additionally, the tolerance of bromo substituents enables further derivatization of the products.
