Determination of the Biological Activity of Insulin and Its Analogues in Animals
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PV Shadrin, LV Simutenko…
Regulatory …, 2022
vedomostincesmp.ru
In recent years, there has been a tendency to equate the results of insulin testing by physicochemical methods with its biological activity. However, it should be emphasised that the effectiveness of insulin preparations can be judged only by the reaction of the whole organism, ie by the hypoglycaemic action, which is a composite indicator. The determination of the biological activity of insulin has become especially relevant with the pharmaceutical market entry of insulin bio similars, which are practically not analogous to the original …
