Gene–environment interactions in the pathogenesis of cardiovascular disease: Risk factors
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S Ahmad, G Rukh
Nature Reviews Cardiology, 2025
nature.com
… Gene–environment interactions (G×E), which can be defined as the combined effect of genetic predisposition and environmental influence, differ from their additive effects, and understanding these interactions is important for devising prevention and therapeutic strategies. … Looking back, the landmark study by Marenberg and colleagues did not merely lay the foundation for the field of CVD genetics; it also profoundly reshaped our understanding of how genetic predisposition and environmental factors interact in the …
