Accelerating innovation in peptide synthesis through continuous-flow
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S Fuse
Organic & Biomolecular Chemistry, 2025
pubs.rsc.org
Peptide-based pharmaceuticals, a representative class of medium-sized molecule drugs, have now surpassed 110 approved compounds. Their significance is also increasing in fields such as agrochemicals and functional materials. Consequently, there is a strong demand for chemical synthesis methods that generate less waste, require shorter reaction times, are more cost-effective, and utilize reagents and solvents with lower environmental impact. For more than half a century, continuous-flow synthesis—where the reaction takes …
