Stereoselective and stereospecific reactions. III. Benzoylation, cyclization, and epimerization of diols.
DOI:
文献链接: https://academic.oup.com/bcsj/article-abstract/49/2/510/7355269?redirectedFrom=fulltext
其他信息:
O Mitsunobu, J Kimura, K Iiizumi…
Bulletin of the Chemical …, 1976
jlc.jst.go.jp
The benzoylation of various classes of diols by means of diethyl azodicarboxylate (1) and triphenylphosphine (2) was carried out at room temperature. When primary–secondary diols were treated with an equimolar amount of benzoic acid (3) in the presence of 1.5 molar equivalents of 1 and 2, reaction mainly Occurred at their primary hydroxyl functions. Secondary–secondary diols gave mono-and dibenzoylated products or cyclic ethers. The course of the reactions depends on the structure of diols used. Thus, intermolecular …
