Chlorhexidine or povidone-iodine solution irrigation versus saline irrigation for the prevention of postoperative infections in primary total joint arthroplasty: a systematic …
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E Machinski, VF da Cruz, RAS Conde…
The Journal of …, 2025
Elsevier
Background This study evaluated the effectiveness of antiseptic irrigation solutions, specifically chlorhexidine, and povidone-iodine, compared to normal saline after primary total joint arthroplasty in preventing periprosthetic joint infection (PJI). Methods Adhering to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, we searched MEDLINE, Embase, and the Cochrane Library databases for studies comparing the use of different intraoperative irrigation following primary total hip arthroplasty and total …

