Primary care physicians play a crucial role in diagnosing and managing rare eosinophilic diseases: HES and EGPA
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M Shum, O Gewurz-Singer, J Silver…
Frontiers in Medicine, 2025
frontiersin.org
Hypereosinophilic syndrome (HES) and eosinophilic granulomatosis with polyangiitis (EGPA) are chronic eosinophilic diseases with serious multisystem manifestations. Patients with HES or EGPA often fail to receive a timely diagnosis, and while these conditions are considered rare, frequent under-recognition indicates that their true prevalence likely exceeds current estimates. Increased primary care physician (PCP) awareness of these systemic eosinophilic conditions and the “red flags” that should trigger referral will help more …

