Comparative effects of drugs for adults with overweight or obesity: systematic review and network meta-analysis
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K Nong, Q Shi, X Xie, Y Wang, A Agarwal, GH Guyatt…
bmj, 2026
bmj.com
Objective To provide an up-to-date evidence summary about the comparative benefits and harms of drugs for adults with overweight or obesity to inform decision making for policymakers, payers, clinicians, and patients. Design Systematic review and network meta-analysis of 24 outcomes using frequentist random effects models and bayesian dose-response models, the GRADE (Grading of Recommendations Assessment, Development, and Evaluation) approach, and the Cochrane Risk of Bias 2 tool. Data sources Medline …

