Heparin-induced antibodies and cardiovascular risk in patients on dialysis
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LM Asmis, JB Segal, LC Plantinga…
… and haemostasis, 2008
thieme-connect.com
The clinical relevance of heparin-induced antibodies (HIA) in the absence of thrombocytopenia remains to be defined. The aims of this study were (i) to determine the prevalence of HIA in patients treated by dialysis,(ii) to determine the prevalence of thrombocytopenia and heparin-induced thrombocytopenia (HIT), and (iii) to test whether HIA are associated with adverse outcomes. Sera from 740 patients treated by hemodialysis (HD, n= 596) and peritoneal dialysis (PD, n= 144) were tested for HIA (IgG, IgA or IgM) by masked …
