The hammerhead ribozyme: structure, catalysis, and gene regulation
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WG Scott, LH Horan, M Martick
Progress in molecular biology and …, 2013
Elsevier
The hammerhead ribozyme has long been considered a prototype for understanding RNA catalysis, but discrepancies between the earlier crystal structures of a minimal hammerhead self-cleaving motif and various biochemical investigations frustrated attempt to understand hammerhead ribozyme catalysis in terms of structure. With the discovery that a tertiary contact distal from the ribozyme