期刊论文The set point of parathyroid hormone stimulation by calcium is normal in progressive renal failure复制

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H Cardinal, JH Brossard, L Roy…
The Journal of …, 1998
academic.oup.com
An increased set point of PTH stimulation by ionized calcium (Ca ) has been observed in renal failure patients with severe secondary hyperparathyroidism. The extension of this concept to all renal failure patients has remained problematic, even if it could explain elevated PTH levels in the absence of other biochemical abnormalities. We were particularly interested in seeing whether the concept could fit patients with progressive renal failure (PRF). To achieve this, we studied 26 normals (N), 9 patients with PRF, and 12 …