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[Dynamics of the biosynthesis of nystatin components by Act. noursei, strain 153 under controlled culture conditions]复制

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文献链接: https://pubmed.ncbi.nlm.nih.gov/7271252复制

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PMID: 7271252
作者: M A Malkov; L E Fadeeva; M A Malkov; M A Malkov; L E Fadeeva
摘要: The ratio of the nystatin components produced under various cultivation conditions was studied. It was found to change during the greater part of the fermentation period and depend on the carbohydrate content in the medium. Under the conditions of the uncontrolled batch process the ratio of components A1 and A2 during the first 36 hours of the cultivation changed from 7.2 to 6.2. When the rate of the antibiotic synthesis was maximum (42 - 72 hours), the ratio of A1 and A2 components was practica...

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