Novel approaches to enhance pulmonary delivery of proteins and peptides
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DOI:
文献链接: https://pubmed.ncbi.nlm.nih.gov/18204175
其他信息:
PMID: 18204175
作者: G Scheuch; R Siekmeier; G Scheuch; G Scheuch; R Siekmeier
摘要: In the last two decades, large efforts have been made to develop safe methods for the delivery of proteins and peptides via the lungs into blood circulation for treatment of systemic diseases. For this purpose, a number of biophysical and physiological parameters have to be considered, such as particle diameter, particle density, hygroscopicity, electrical charge, chemical properties of the substance and age, pulmonary diseases, breathing pattern, all of which affect the mechanisms of pulmonary ...
