Effects of estriol administration on human postmenopausal endometrium.
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C Montoneri, G Zarbo, A Garofalo…
… Obstetrics & Gynecology, 1987
europepmc.org
Forty eight women with atrophic endometrium were treated with estriol, 1 mg twice daily, by mouth for a minimum of 10 days and a maximum of 25 days. Vaginal hysterectomy was then performed and specimens were examined histologically. Results showed that estriol produces endometrial hyperplasia in 70.8% of the examined women; only 29.2% of the patients retained atrophic endometrium after treatment.
