Clinical pharmacokinetics of aspirin
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DOI:
文献链接: https://pubmed.ncbi.nlm.nih.gov/724339
其他信息:
PMID: 724339
作者: G Levy; G Levy; G Levy
摘要: Aspirin is very rapidly absorbed from the gastrointestinal tract when administered as a solution, and somewhat more slowly when administered in tablets. It is rapidly hydrolyzed in the body to salicylic acid; the plasma concentration of the latter must be maintained within a relatively narrow range to obtain an adequate anti-inflammatory effect and to minimize systemic adverse effects. The two major pathways of salicylate elimination, i.e., formation of salicyluric acid and salicyl phenolic gluc...
