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Synthesis and fungicidal evaluation of novel chalcone-based strobilurin analogues复制

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PL Zhao, CL Liu, W Huang, YZ Wang…
Journal of agricultural …, 2007
ACS Publications
Strobilurin derivatives have become one of the most important classes of agricultural fungicide due to a novel action mode, wide fungicidal spectrum, lower toxicity toward mammalian cells, and environmentally benign characteristics. To discover new strobilurin analogues with high activity against resistant pathogens, a series of new chalcone-based strobilurin derivatives are designed and synthesized by integrating a chalcone scaffold with a strobilurin pharmacophore. The preliminary bioassay showed that some of the chalcone …

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