Discovery of ORIC-533, an Orally Bioavailable CD73 Inhibitor That Maintains Activity in High AMP Environments to Reverse Tumor Immunosuppression
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DOI: https://doi.org/10.1021/acs.jmedchem.5c02153
文献链接: https://pubs.acs.org/doi/10.1021/acs.jmedchem.5c02153
其他信息:
出版社: American Chemical Society (ACS)
作者: Jared T. Moore; Hiroyuki Kawai; Brian R. Blank; Kejia Wu; Chien-Hung Yeh; Liusheng Zhu; Johnny D. Pham; Yosup Rew; John Eksterowicz; Sumeet Salaniwal; Dena Sutimantanapi; Robert Warne; Natalie Yuen; Todd C. Metzger; Brenda Chan; Tom Huang; Xi Chen; Yuping Chen; Frank Duong; Wayne Kong; Jae H. Chang; Jessica D. Sun; Tatiana Zavorotinskaya; Quiping Ye; Mohammad A. Al-Sayah; Erica Jackson; Melissa R. Junttila; Valeria R. Fantin; Chudi O. Ndubaku; Daqing Sun; Xiaohui Du; Lori S. Friedman
全文下载地址: https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5c02153
