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Specificity of EIA immunoassay for complement factor Bb testing复制

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文献链接: https://pubmed.ncbi.nlm.nih.gov/21500731复制

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PMID: 21500731
作者: Igor Y Pavlov; Nikol De Forest; Julio C Delgado; Igor Y Pavlov; Igor Y Pavlov; ...
摘要: Background: During the alternative complement pathway activation, factor B is cleaved in two fragments, Ba and Bb. Concentration of those fragments is about 2 logs lower than of factor B present in the blood, which makes fragment detection challenging because of potential cross-reactivity. Lack of information on Bb assay cross-reactivity stimulated the authors to investigate this issue.

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