The Avian EB66(R) Cell Line, Application to Vaccines, and Therapeutic Protein Production
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DOI:
文献链接: https://pubmed.ncbi.nlm.nih.gov/21502045
其他信息:
PMID: 21502045
作者: Stephen W Brown; Majid Mehtali; Stephen W Brown; Stephen W Brown; Majid Mehtali
摘要: Embryonated chicken eggs and primary chicken embryo fibroblasts (CEFs) have been used for decades as a means of manufacturing human and veterinary vaccines. However, these egg and CEF-based production systems are associated with many serious limitations in terms of their regulatory acceptability, production capacity, and supply chain risks. The development of a safer, cheaper, and more efficient cell substrate for vaccine production would represent a significant business advantage for vaccine ma...
