期刊论文Androgen receptor modulator compounds and methods复制

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JP Edwards, R Higuchi, TK Jones…
US Patent …, 2000
Google Patents
The present invention is directed to compounds, pharma ceutical compositions, and methods for modulating pro cesses mediated by androgen receptors (AR). More particularly, the invention relates to non-Steroidal com pounds and compositions which are high affinity, high Specificity agonists, partial agonists (ie, partial activators and/or tissue-specific activators) and antagonists for andro gen receptors. Also provided are methods of making Such compounds and pharmaceutical compositions, as well as critical intermediates used in …