Mass spectrometry-based methods for biofluid biomarkers for progressive diseases: amyloid peptides and dystrophins
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M Niwa, K Noda, Y Kobayashi, I Kageyama…
Bioanalysis, 2025
Taylor & Francis
ABSTRACT Purpose Using two diseases, Alzheimer's disease and muscular dystrophy as examples, in which many resources have been invested, trends in bioanalytical techniques for detection of peptide or protein biomarkers using mass spectrometry are reviewed using Web of Science database. Amyloid beta peptides have been used to detect Alzheimer's disease, and peptides obtained by tryptic digestion of dystrophin have been used to detect muscular dystrophy. Based on the recent interest in peripheral blood analysis, literature …
