Pretraining a foundation model for small-molecule natural products
1. 文件大小不能超过300M, 允许上传文档或压缩包等
2. 请确保上传文献的真实性、完整性，不得对原文做任何修改
注: 所有应助的资源仅供学习交流使用, 不得违反相关法律法规
DOI:
文献链接:
其他信息:
Y Ding, B Qiang, S Li, Y Zhou, J Yu, Q Li…
Nature Machine …, 2026
nature.com
Natural products, as metabolites from microorganisms, animals or plants, exhibit diverse biological activities, making them crucial for drug discovery. Nowadays, existing deep-learning methods for natural products research primarily rely on supervised learning approaches designed for specific downstream tasks. However, such one-model-for-a-task paradigm often lacks generalizability and leaves substantial room for performance improvement. Additionally, existing molecular characterization methods are not well-suited …
