[Efficacy testing of stabilizing agents in epinephrine model solutions. 19: Stability of drugs and preparations]
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DOI:
文献链接: https://pubmed.ncbi.nlm.nih.gov/6844380
其他信息:
PMID: 6844380
作者: H Wollmann; G Raether; H Wollmann; H Wollmann; G Raether
摘要: The efficiency of 54 stabilizers was tested on epinephrine solutions using a selection-combination method. The addition of only one antioxidant produces but slight improvements in stability. Maximal additive activity is achieved by the combination of two antioxidants. Superadditive effects (which are necessary for considerable prolongation of the time of applicability of aqueous epinephrine solutions) are obtained by the combination of antioxidants of different modes of action and a discolourati...