A Photoenzymatic Pathway for Gram‐Scale Synthesis of 25‐Hydroxyvitamin D3
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C Xu, Y Huang, H Li, Q Shen, F Wang, J Shi…
…, 2025
Wiley Online Library
Vitamin D and its analogues play a crucial role in promoting the well‐being of both humans and animals. However, the current synthesis of this vital class of nutrients heavily relies on chemical transformations, which suffer from low step‐and atom‐efficiency due to lengthy synthetic pathways. To enhance sustainability in the chemical industry, it is necessary to develop alternative synthetic processes. Herein, we present a photoenzymatic approach for synthesizing 25‐hydroxyvitamin D3 from 7‐dehydrocholesterol. In this sequential synthesis …
