Strategies for conducting ADME studies during lead generation in the drug discovery process
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DOI:
文献链接: https://pubmed.ncbi.nlm.nih.gov/21154143
其他信息:
PMID: 21154143
作者: Jeffrey W Cramer; Brian E Mattioni; Kenneth A Savin; Jeffrey W Cramer; Jeffrey W Cramer; ...
摘要: Although the benefit of early ADME screening is widely recognized in the pharmaceutical industry, the implementation of this paradigm is often performed with insufficient resources and poor collaboration between functions. Dedicated and consistent integration efforts of ADME knowledge during the lead generation (LG) phase of drug discovery enables informed resourcing decisions and also increases the quality of initial starting points for discovery projects. To facilitate the efficient and consis...
