Elastin-like polypeptide and triclosan-modified PCL membrane provides aseptic protection in tissue regeneration
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X Peng, Y Wang, S Liu, J Zhang, L Liu, Q Liu, X Li…
Materials Today Bio, 2025
Elsevier
Tissue regeneration is a spatiotemporally ordered multidimensional process involving hierarchical structures, vascularization, and metabolic-immune properties, while injury often triggers structural disorganization, inflammation, metabolic dysfunction, and mechanical impairment. Based on these findings, we designed a functionalized polycaprolactone (PCL) porous scaffold loaded with biocompatible elastin and the antibacterial drug triclosan, which specifically inhibits the growth of methicillin-resistant Staphylococcus aureus (MRSA). Using …
