期刊论文Neuroblastoma metastatic to the central nervous system. The Memorial Sloan-kettering Cancer Center Experience and A Literature Review复制

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文献链接: https://pubmed.ncbi.nlm.nih.gov/11301399复制

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PMID: 11301399
作者: K Kramer; B Kushner; G Heller; N K Cheung; K Kramer; ...
摘要: Background: The central nervous system (CNS) can be a sanctuary site for cancer cells, because the blood-brain barrier impedes penetration of most chemotherapeutic agents. The authors hypothesized that, with improved survival from childhood metastatic neuroblastoma (NB), the incidence of CNS (intraparenchymal and leptomeningeal) spread may increase. They undertook this study to assess the frequency of CNS NB, to analyze risk factors and treatment options, and to review the ...