期刊论文Topical Clascoterone for Acne Vulgaris.复制

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NE Burma, TE Woo, L Parsons
Skin Therapy Letter, 2022
europepmc.org
… Existing systemic therapies target hormonal pathways to mitigate acne lesions; however,
their use is limited to the female population and associated with systemic adverse effects.
Clascoterone is the first topical therapy to target the hormonal pathogenesis of acne
approved to treat acne vulgaris. In two identical phase 3 trials, clascoterone showed
favorable efficacy over placebo in treating acne, with higher treatment success and a
greater reduction in acne lesions. Large scale trials are required to assess the efficacy of …