Targeting Triglycerides: The Rise of Apolipoprotein C3 and Angiopoietin-Like Protein 3 Inhibitors: T. Mansoor et al.靶向甘油三酯：载脂蛋白 C3 与血管生成素样蛋白 3 抑制剂的崛起：T. Mansoor 等人
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DOI:
文献链接: https://pubmed.ncbi.nlm.nih.gov/40652105/
其他信息:
T Mansoor, V Nambi, S Parikh, A Misra…
American Journal of …, 2025
Springer
Hypertriglyceridemia has been proposed as a risk factor for atherosclerotic cardiovascular disease (ASCVD). Triglycerides (TG) are viewed as a marker for remnant cholesterol in triglyceride-rich lipoproteins, as this remnant cholesterol has been identified as a causal risk factor for ASCVD. The limited number of effective treatments for elevated TG has fueled the search for novel pharmacotherapy options, and multiple medication classes are being explored. Apolipoprotein C3 (APOC3) and angiopoietin-like protein 3 (ANGPTL3) are …
