Efficacy and safety of butylphthalide in patients with acute ischemic stroke: a randomized clinical trial
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A Wang, B Jia, X Zhang, X Huo, J Chen, L Gui…
JAMA …, 2023
jamanetwork.com
Importance DL-3-n-butylphthalide (NBP) is a drug for treating acute ischemic stroke and may play a neuroprotective role by acting on multiple active targets. The efficacy of NBP in patients with acute ischemic stroke receiving reperfusion therapy remains unknown. Objective To assess the efficacy and safety of NBP in patients with acute ischemic stroke receiving reperfusion therapy of intravenous thrombolysis and/or endovascular treatment. Design, Setting, and Participants This multicenter, double-blind, placebo-controlled, parallel …
