期刊论文Analyzing a calcium-dependent UV response that results in a global chromatin compaction in mammalian cells复制

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R Sinha Roy
2023
tdl-ir.tdl.org
Genomic integrity is challenged every day by both endogenous and exogenous stresses. Once DNA gets damaged, a series of events follow, starting with recognizing the damage by accessing it, then processing and repairing the damaged DNA, and eventually restoring the lesion area to its pre-damage state. However, the structural change in the global chromatin in response to UV radiation and the etiology of these changes are not well known. To visualize a global chromatin structural changes upon UVB radiation, we used a fluorometric …