Ursodeoxycholic acid has no influence on function after restorative proctocolectomy in ulcerative colitisIF 6.6SCIEJCR Q1医学1区Top
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Tan, Morton, Bain, Keighley
Alimentary pharmacology & …, 1999
Wiley Online Library
Background: Poor pouch function is associated with impaired bile acid absorption and increased faecal loss of bile acids. Bile acid replacement therapy might therefore be of clinical benefit, provided that diarrhoea is not aggravated by therapy. Aim: To investigate the role of exogenous bile acid therapy in patients with poor pouch function after restorative proctocolectomy for ulcerative colitis. Patients and methods: Twenty ulcerative colitis patients with poor pouch function (score> 4 on a 12‐point score) were recruited for inclusion …
