期刊论文Pharmacokinetics of depot medroxyprogesterone acetate contraception复制

DOI:复制

文献链接: https://pubmed.ncbi.nlm.nih.gov/8725700复制

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PMID: 8725700
作者: D R Mishell Jr; D R Mishell Jr; D R Mishell Jr
摘要: Depot medroxyprogesterone acetate (DMPA) is an aqueous suspension of 17-acetoxy 6-methyl progestin administered by intramuscular injection for long-term contraception. This highly effective injectable formulation of medroxyprogesterone acetate (MPA) has a prolonged duration of action since the progestin is released slowly from the muscle. MPA is detected in the serum within 30 minutes after an injection of 150 mg. Serum concentrations vary between individual women but generally plateau at about ...