Multitasking by exploitation of intracellular transport functions: the many faces of FcRn
1. 当前求助状态已完结, 请及时下载应助文件
2. 系统将在 2026-04-07 14:26:02 删除文件
注: 所有应助的资源仅供学习交流使用, 不得违反相关法律法规
DOI:
文献链接:
其他信息:
ES Ward, RJ Ober
Advances in immunology, 2009
Elsevier
Abstract The MHC Class I-related receptor, FcRn, transports antibodies of the immunoglobulin G (IgG) class within and across a diverse array of different cell types. Through this transport, FcRn serves multiple roles throughout adult life that extend well beyond its earlier defined function of transcytosing IgGs from mother to offspring. These roles include the maintenance of IgG levels and the delivery of antigen in the form of immune complexes to degradative compartments within cells. Recent studies have led to …
