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Iron protein succinylate: preclinical safety assessment复制

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文献链接: https://pubmed.ncbi.nlm.nih.gov/8458676复制

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PMID: 8458676
作者: R Forster; R Forster; R Forster
摘要: In this brief review the preclinical safety studies on iron protein succinylate (synonym: ITF 282) are presented. Iron protein succinylate is an iron-protein complex, in which iron is present in ferric form. It has been developed for oral iron-supplementation therapy and is characterized by a very favorable tolerability profile. The acute toxicity of iron protein succinylate to rodents is very low, indicating a substantial margin of safety with respect to accidental child poisonings. In chronic ...

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