期刊论文Stability of glycopyrrolate injection at ambient temperature and 4 deg C in polypropylene syringes复制

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文献链接: https://pubmed.ncbi.nlm.nih.gov/23979508复制

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PMID: 23979508
作者: Meredith L Storms; James T Stewart; Flynn W Warren; Meredith L Storms; Meredith L Storms; ...
摘要: The stability of 0.2-mg/mL glycopyrrolate injection in 6-mL polypropylene syringes stored at ambient temperature and at 4 deg C for up to 90 days was investigated. A high-performance liquid chromatographic stability-indicating assay was used to determine the concentration level of glycopyrrolate injection 0, 1, 4, 7, 15, 30, 45, 60, and 90 days after preparation of the syringes. Benzyl alcohol, which was added as a preservative, did not interfere with the assay. The injection in plastic syringes...