Aldosterone and mineralocorticoid receptors in regulation of the cardiovascular system and pathological remodelling of the heart and arteries.
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D Sztechman, K Czarzasta…
Journal of Physiology …, 2018
jpp.krakow.pl
… Specifically, selective overexpression of 11-HSD2 in cardiomyocytes, which leads to selective activation of MRs by aldosterone, resulted in cardiac hypertrophy, fibrosis, heart failure …