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Transplantation of subretinal stem cell–derived retinal pigment epithelium for stargardt disease: A Phase I Clinical Trial复制

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DOI:复制

文献链接: https://journals.lww.com/retinajournal/abstract/2023/02000/transplantation_of_subretinal_stem_cell_derived.12.aspx?context=latestarticles复制

其他信息:

RAB Fernandes, FH Lojudice, LZ Ribeiro, NFS da Cruz…
Retina, 2023
journals.lww.com
Purpose: To assess the safety of injecting human embryonic stem cell retinal pigment epithelial cell dose to treat Stargardt disease. Methods: In this prospective, Phase I clinical trial, human embryonic stem cell retinal pigment epithelial cells in suspension were injected into the subretinal space in eyes with the worse best-corrected visual acuity (BCVA). After vitrectomy/posterior hyaloid removal, a partial retinal detachment was created and the human embryonic stem cell retinal pigment epithelial cells were administered …

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