Antibody Therapies for Alzheimer's Disease: A New Strategy for Targeted Therapy and Blood–Brain Barrier Delivery
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X Feng, H Wang
ACS Chemical Neuroscience, 2025
ACS Publications
Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive cognitive impairment and neuronal loss, with pathological hallmarks including Aβ plaque deposition and tau tangles. At present, the early diagnosis and treatment of AD still face great challenges, such as limited diagnostic methods, difficulty in blood–brain barrier (BBB) penetration, complex disease mechanisms, and lack of highly effective targeted therapies. Antibody drugs have shown broad prospects in the field of AD due to their high specificity …