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Higher versus lower phosphate targets for patients undergoing in-center hemodialysis: a randomized controlled trial复制

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D Edmonston, T Isakova, LM Dember…
Journal of the …, 2024
journals.lww.com
Background: Serum phosphate targets in maintenance hemodialysis are based on observational studies. The HiLo trial aimed to compare the effect of a higher versus a lower phosphate target on clinical events in patients receiving maintenance hemodialysis. Methods: HiLo was a pragmatic, multicenter randomized trial that compared higher (≥ 6.5 mg/dl;“Hi”) versus lower (

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