Clinical pharmacokinetics of drugs in patients with heart failure: an update (part 1, drugs administered intravenously)
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R Ogawa, JM Stachnik, H Echizen
Clinical pharmacokinetics, 2013
Springer
Heart failure is one of the leading causes of death in developed countries, and its prevalence is expected to increase further in the coming years. While the pharmacokinetic changes observed in patients with heart failure have been reviewed twice in Clinical Pharmacokinetics, approximately a quarter century has passed since the latest article was published in 1988. Since then, many important classes of agents (eg ACE inhibitors, angiotensin receptor antagonists and inotropes) have been introduced for the treatment of …

