18407 Improvement of short-term outcome of mild to moderate atopic dermatitis using a combination treatment of crisaborole ointment 2% and a concomitant topical …
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DOI:
文献链接: https://www.jaad.org/article/S0190-9622(20)32032-6/abstract
其他信息:
T Schlesinger, C Nduaka, T Elstrom
Journal of the American Academy of …, 2020
jaad.org
Background: Atopic dermatitis (AD) also known as atopic eczema is a chronic inflammatory skin disease that is characterized by intense itching and recurrent eczematous lesions. Although it most often starts in infancy and affects two of ten children, it is also highly prevalent in adults. Current topical treatments for AD have not changed in over 15 years and are associated with safety concerns. In AD, overactivity of phosphodiesterase 4 (PDE4), leads to inflammation and disease exacerbation. Combination therapy is known to be …
