期刊论文Data-driven Dynamic Control Scheme for Antibody Producing CHO Cell Cultures in Fed-batch复制

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N Gangadharan
2023
repository.cam.ac.uk
Effective process control is a basic requirement for biopharmaceutical manufacturing to achieve high efficiency and enhanced quality control. High non-linearity and uncertainties associated with bioprocesses challenge the ability of traditional controllers to deliver satisfactory performance, thereby creating a need for advanced model based control strategies for efficient bioprocess control. Unlike the chemical or traditional pharmaceutical sector, bioprocess control is a complex process that involves controlling the behaviour of …